Varivax Drug Interactions

Vaccination should be deferred for at least 5 months following blood or plasma transfusions, or administration of immune globulin or varicella zoster immune globulin (VZIG).
Following administration of Varicella Virus Vaccine Live (Varivax) (Refrigerated), any immune globulin including VZIG should not be given for 2 months thereafter unless its use outweighs the benefits of vaccination.
Vaccine recipients should avoid use of salicylates for 6 weeks after vaccination with Varicella Virus Vaccine Live (Varivax) (Refrigerated) as Reye syndrome has been reported following the use of salicylates during wild-type varicella infection.
Results from clinical studies indicate that Varicella Virus Vaccine Live (Varivax) (Refrigerated) can be administered concomitantly with M-M-R II (Measles, Mumps, and Rubella Virus Vaccine Live), diphtheria and tetanus toxoids and pertussis vaccine adsorbed and Haemophilus influenzae type b conjugate combined vaccine, or Haemophilus influenzae type b Conjugate (Meningococcal Protein Conjugate) and Hepatitis B (Recombinant) combined vaccine. If Varicella Virus Vaccine Live (Varivax) (Refrigerated) is not given concomitantly with M-M-R II, a 1-month interval between the 2 live virus vaccines should be observed.
Limited data from an experimental product containing varicella vaccine suggest that Varicella Virus Vaccine Live (Varivax) (Refrigerated) can be administered concomitantly with DTaP (diphtheria, tetanus, acellular pertussis) and PedvaxHIB [Haemophilus b Conjugate Vaccine (Meningococcal Protein Conjugate)] using separate sites and syringes and with OPV (oral poliovirus vaccine).