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Co-amoxiclav possesses the characteristic low toxicity of the penicillin group of antibiotics. Periodic assessment of organ system functions, including renal, hepatic and hematopoietic function, is advisable during prolonged therapy. A high percentage of patients with mononucleosis who received ampicillin develop a skin rash. Thus, ampicillin class antibiotics are excreted in milk.
Therefore caution should be exercised when Co-amoxiclav is administered to a nursing woman.
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