Ureleve Dosage/Direction for Use

The recommended dose is 8 mg orally once daily with a meal. Or as prescribed by the physician.
Patients who have difficulty swallowing pills and capsules may carefully open the Silodosin capsule and sprinkle the powder inside on a tablespoon of applesauce. The applesauce should be swallowed immediately (within 5 minutes) without chewing and followed with an 8 oz glass of cool water to ensure complete swallowing of the powder. The applesauce used should not be hot, and it should be soft enough to be swallowed without chewing. Any powder/applesauce mixture should be used immediately (within 5 minutes) and not stored for future use. Subdividing the contents of a Silodosin capsule is not recommended.
Dosage Adjustment in Special Populations: Renal impairment: Silodosin is contraindicated in patients with severe renal impairment (CrCl <30 mL/min). In patients with moderate renal impairment (CrCl 30-50 mL/min), the dose should be reduced to 4 mg once daily taken with a meal. No dosage adjustment is needed in patients with mild renal impairment (CrCl 50-80 mL/min).
Hepatic impairment: Silodosin has not been studied in patients with severe hepatic impairment (Child-Pugh score ≥10) and is therefore contraindicated in these patients. No dosage adjustment is needed in patients with mild or moderate hepatic impairment.