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Ursodeoxycholic acid should not be given to patients with peptic ulcer disease, inflammatory bowel disease, or chronic liver disease. Its use should be avoided in pregnancy.
General Precautions: The following patients should see a physician before taking this drug: Patients with severe pancreatic disease; patients with choledocholithiasis; patients with variceal bleeding, hepatic encephalopathy, ascites and those in need of an urgent liver transplantation.
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