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Celecoxib should not be used in patients with severe hepatic impairment. Therapy should be withdrawn if signs and symptoms of hepatic toxicity develops. Celecoxib should not be given to patients with a history of hypersensitivity to sulfonamides.
Celecoxib should not be used in patients with liver dysfunction, impaired renal function, dehydration, anemia, pre-existing asthma and pregnant.
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