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Pregnancy: There are no data on use of Ceftriaxone in pregnant women. Ceftriaxone crosses the placenta. Animal studies indicate no reproductive toxicity. As a precautionary measure, Ceftriaxone should only be used during pregnancy after benefit/risk assessment by the physician in charge, especially during the first trimester.
Lactation: Ceftriaxone is excreted in low concentrations in breast milk. Caution should be exercised when prescribing to breast-feeding women. Diarrhoea and fungal infection of the mucous membrane could occur in the breast-fed infant, so that nursing might have to be discontinued. The possibility of sensitization should be born in mind.
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