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The following side effects have been reported: Gastrointestinal system: Nausea; vomiting; dry mouth; heartburn; constipation.
Central Nervous System and Psychiatric: Fatigue; sedation; drowsiness; confusion; hallucinations; seizures (see Warnings).
Other: Sweating (especially when intravenous administration is too rapid); skin rashes; bradycardia; tachycardia; flushing; bronchospasm; angioedema; syncope, anaphylaxis and anaphylactic reactions have been reported. These reactions may occur after the first dose. Postural hypotension or cardiovascular collapse has been observed, potential for Toxic Epidermal Necrolysis and Steven-Johnson syndrome. Tramadol should not be used for the treatment of minor pain.
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