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In case of incorrect administration (dosage and rate), signs of hypervolemia and acidosis may be observed. Hyperglycemia, glycosuria, and a hyperosmolar syndrome may occur with excessive glucose infusion. A too rapid infusion of amino acid may result in nausea, vomiting and shivering. In such cases, discontinue the infusion immediately.
In case of fat overdosing (an abnormal triglyceride rise under infusion of fat) causing special reactions (general symptoms such as fever or evocating an hemodynamic instability, emesis, algia, liver function abnormalities, hepato- or splenomegaly, hemostasis disorders, hyperlipidemia, hypersensitivity) fat infusion should be stopped or if necessary, continued at a reduced dosage.
In some serious cases, haemodialysis, haemofiltration or haemodiafiltration may be necessary.
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