Thydin Special Precautions

Dose must be carefully monitored and titrated as it is necessarily given to a certain patient. When given to elderly and in patients with cardiovascular disease, high initial dose or rapid dose titration may exacerbate symptoms of cardiovascular disease. For patients with myxedema, low dose should initiate replacement therapy with slow dosing increments since these patients have increased sensitivity for thyroid hormones.
In pituitary hypothyroidism (secondary hypothyroidism), institute corticosteroid replacement therapy prior to Levothyroxine replacement therapy to prevent acute adrenal insufficiency.
Levothyroxine therapy affects thyroid function test; however, Thyroid Stimulating Hormone (TSH) test should be performed to check the levels of T3 and T4 for dose titration of Levothyroxine Sodium Tablet (Thydin). It should be noted that slight increase of T4 level is required to guarantee a normal level T3.
Patients with euthyroid non-autonomous goiter can only be treated if the TSH response is not affected.