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Anagrelide should be used only with caution and after a positive risk/benefit evaluation in patients with cardiovascular, renal or liver diseases.
When high single doses (5 mg) are administered hypotension and dizziness can occur because of vasodilatation, following single doses of 2 mg a small and reversible decrease in blood pressure can occur.
Haematological parameters (in particular haematocrit and leukocyte count), renal and liver parameters should be controlled in regular intervals during the use of Anagrelide.
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