Tamsolin Special Precautions

Before therapy with tamsulosin HCl is initiated, the patient should be examined in order to exclude the presence of other conditions which can cause the same symptoms as BPH. Digital rectal examination and when necessary, determination of prostate specific antigen (PSA) should be performed before treatment and at regular intervals afterwards.
Patients with end-stage renal disease (CrCl <10 mL/min/1.73 m²) should be approached with caution as these patients have not been studied.
Patients should be advised about the possibility of priapism as a result of treatment with tamsulosin and other similar medications. Patient should be informed that this reaction is extremely rare, but if not brought to immediate medical attention, can lead to permanent erectile dysfunction (impotence).
Intraoperative floppy iris syndrome (IFIS) has been observed during cataract surgery in some patients taking or who have previously been treated with α₁-adrenoceptor antagonists.
Avoid drinking alcohol, it may increase dizziness caused by tamsulosin HCl.
Discontinue if angina pectoris occur.
Effects on the Ability to Drive or Operate Machinery: As with other α₁-blockers, reduction in blood pressure can occur in individual cases during treatment with tamsulosin HCl, as a result of which, very rarely, syncope can occur. At the 1st signs of orthostatic hypotension (dizziness, weakness), the patient should sit or lie down until the symptoms have disappeared. Patients so affected should not drive or operate machinery.