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Tacroz: Use in Pregnancy: Pregnancy Category C: There are no adequate and well-controlled studies of topically administered Tacrolimus in pregnant women. Tacrolimus is transferred across the placenta. Tacrolimus (Tacroz) ointment should be used during pregnancy only if the potential benefit to the mother justifies a potential risk to the fetus.
Use in Lactation: Tacrolimus is excreted in human milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
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