Levocetirizine: Symptoms: Symptoms of overdose may include drowsiness in adults. In children, agitation and restlessness may initially occur, followed by drowsiness.
Management of overdoses: There is no known specific antidote to levocetirizine.
Should overdose occur, symptomatic or supportive treatment is recommended.
Gastric lavage may be considered shortly after ingestion of the drug.
Levocetirizine is not effectively removed by haemodialysis.
Betamethasone: Symptoms: Acute overdosage with glucocorticosteroids, including betamethasone, is not expected to lead to a life-threatening situation. Except at the most extreme dosages, a few days of excessive glucocorticosteroid dosing is unlikely to produce harmful results in the absence of specific contraindications, such as in patients with diabetes mellitus, glaucoma, or active peptic ulcer, or in patients on medications such as digitalis, coumarin-type anti-coagulants or potassium-depleting diuretics.
Treatment: In the event of overdosage, consultation with a poison control center should be considered. Consider standard measures to remove any unabsorbed drug, e.g. gastric lavage. Otherwise complications resulting from the metabolic effects of the corticosteroid or from deleterious effects of the basic or concomitant illnesses or resulting from drug interactions should be handled as appropriate.
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