Sign Out
Hypersensitivity to the active substance or any of the excipients.
Active peptic ulceration or active gastrointestinal (GI) bleeding.
Patients who have experienced bronchospasms, acute rhinitis, nasal polyps, angioneurotic edema, urticaria, or allergic-type reactions after taking acetylsalicylic acid or NSAIDs including COX-2 (cyclooxygenase-2) inhibitors.
Severe hepatic dysfunction (serum albumin <25 g/L or Child-Pugh score 10 ≥ 10).
Estimated renal clearance creatinine <30 mL/min.
Children and adolescents under 16 years of age.
Inflammatory bowel disease.
Congestive Heart Failure (NYHA II-IV).
Patients with hypertension whole blood pressure has not been adequately controlled.
Established ischemic heart disease, peripheral arterial disease and/or cerebrovascular disease.
