Skinoren Gel Dosage/Direction for Use

Method of administration: Cutaneous use.
Dosage regimen: Azelaic acid (Skinoren) gel should be applied to the affected areas of skin twice a day (morning and evening) and rubbed in gently.
Approximately 0.5 g = 2.5 cm (1 inch) of gel is sufficient for the entire facial area.
It is important to continue to use Azelaic acid (Skinoren) gel regularly over the entire period of treatment.
The duration of use of Azelaic acid (Skinoren) gel can vary from patient to patient and also depends on the severity of the skin disorder. In general, a distinct improvement becomes apparent after about 4 weeks. To obtain the best results, Azelaic acid (Skinoren) gel should be used continuously over several months.
In the event of intolerable skin irritation (see Adverse Reactions), the amount of gel per application should be reduced or the frequency of use of Azelaic acid (Skinoren) gel should be reduced to once a day until the irritation ceases. If required, treatment might have to be temporarily interrupted for a few days.
Additional information on special populations: Pediatric Patients: Use in adolescents (12-18 years of age) for the treatment of acne vulgaris. Dose adjustment is not required when Azelaic acid (Skinoren) gel is administered to adolescents aged 12-18 years.