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In the few reports of drug overdosage received, recovery was uneventful, including by a patient who ingested 400 mg tizanidine (Sirdalud).
Symptoms: Nausea, vomiting, hypotension, QT(c) prolongation, dizziness, somnolence, miosis, restlessness, respiratory distress, coma.
Treatment: It is recommended to eliminate the ingested drug by repeated administration of high doses of activated charcoal. Forced diuresis is expected to accelerate the elimination of the drug. Further treatment should be symptomatic.
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