Pink, round, biconvex, uncoated tablet.
Each tablet contains: Thiamine HCl (Vit. B1), USP 100 mg, Pyridoxine HCl (Vit. B6) 20 mg, Cyanocobalamin (Vit. B12) 200 mcg.
This product is a combination of vitamin B complex, necessary for normal growth and in sufficient quantity to ensure stimulation of appetite. Thiamine hydrochloride acts as a coenzyme in carbohydrate metabolism; Pyridoxine hydrochloride is important in the metabolism of amino acids and Cyanocobalamin is needed in nucleic acid synthesis and for normal maturation of red blood cells.
This medicine is a comprehensive metabolic stimulant where nutritional requirements are increased. Specifically indicated in pernicious anemia, beri-beri, certain sensory neuropathies responding to massive doses of vitamin B12, patients with gastrectomy and/or terminal ileal disease, nausea and vomiting in pregnancy, pellagra, anorexia, prevention and treatment of Vitamin B complex deficiencies especially indicated for children as high potency supplement, appetite stimulant and growth factor.
1 to 2 tablets daily, or as prescribed by a physician.
What Should the Patient Do if They Miss a Dose: If dose is missed, take the next dose and the subsequent doses at the usual recommended schedule, i.e., once or twice daily.
Signs and Symptoms of Overdose: Severe sensory neuropathy has been described in patients receiving large doses of pyridoxine (2 to 6 g daily) for periods of 2 to 4 months. However, there have been some case reports with amounts up to about 500 mg daily and prolonged use of even lower doses (about 200 mg daily or less) may also cause sensory peripheral neuropathy.
What to Do When the Patient Has Taken More Than the Recommended Dosage: If patient has taken more than the recommended dosage, consult a doctor.
If patient is allergic/hypersensitive to any component of the product.
Long term therapy with Vitamin B12 must include evaluation of the peripheral blood count and macrocytosis of ½ to 1 year intervals.
Long term use of large doses of pyridoxine is associated with the development of severe peripheral neuropathies.
Pyridoxine reduces the effects of levodopa but this does not occur if a dopa decarboxylase inhibitor is also given. Pyridoxine reduces activity of altretamine. It has also been reported to decrease serum concentrations of phenobarbital and phenytoin. Many drugs may increase requirements for pyridoxine; such drugs include hydralazine, isoniazid, penicillamine, and oral contraceptives.
Absorption of vitamin B12 from the gastrointestinal tract may be reduced by neomycin, aminosalicylic acid, histamine H2-antagonists, omeprazole, and colchicine. Serum concentrations may be decreased by use of oral contraceptives. Many of these interactions are unlikely to be of clinical significance but should be taken into account when performing assays for blood concentrations. Parenteral chloramphenicol may attenuate the effect of vitamin B12 anemia.
Store at temperatures not exceeding 30°C.
Protect from light.
A11EA - Vitamin B-complex, plain ; Used as dietary supplements.
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