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Women of child-bearing potential: Women of child-bearing potential should use appropriate contraceptive measures during treatment.
Pregnancy: There are no or limited amount of data from the use of Ivabradine in pregnant women.
Studies in animals have shown reproductive toxicity. These studies have shown embryotoxic and teratogenic effects. The potential risk for humans is unknown. Therefore, ivabradine is contraindicated during pregnancy.
Breast-feeding: Animal studies indicate that Ivabradine is excreted in milk. Therefore, Ivabradine is contraindicated during breast-feeding.
Women that need treatment with Ivabradine should stop breast-feeding, and choose for another way of feeding their child.
Fertility: Studies in rats have shown no effect on fertility in males and females.
