Sensitrin Dosage/Direction for Use

Adults and Children 12 Years of Age and Older: The recommended dose of Levocetirizine hydrochloride is 5 mg (1 tablet) once daily in the evening. Some patients may be adequately controlled by 2.5 mg (1/2 tablet) once daily in the evening.
Children 6 to 11 Years of Age: The recommended dose of Levocetirizine hydrochloride is 2.5 mg (1/2 tablet) once daily in the evening. The 2.5 mg dose should not be exceeded because the systemic exposure with 5 mg is approximately twice that of adults.
Dosage Adjustment for Renal and hepatic Impairment: In adults and children 12 years of age and older with: Mild renal impairment (creatinine clearance [CL_CR=50-8 mL/min): a dose of 2.5 mg once daily is recommended; Moderate renal impairment (CL_CR=30-50 mL/min): a dose of 2.5 mg once every other day is recommended; Severe renal impairment (CL_CR=10-30 mL/min): a dose of 2.5 mg twice weekly (administered once every 3-4 days) is recommended; End-stage renal disease patients (CL_CR < 10 mL/min) and patients undergoing hemodialysis should not receive Levocetirizine hydrochloride.
No dose adjustment is needed in patients with solely hepatic impairment. In patients with both hepatic and renal impairment, adjustment of the dose is recommended.