Iron is known to decrease the antibiotic action of Tetracyclines and Quinolones. In addition, iron may decrease the absorption of the following medications: Levodopa (a drug used to treat Parkinson's disease); Levothyroxine which is used to treat hypothyroidism; Bisphosphonates (used for treatment of osteoporosis and other bone diseases); Methyldopa (an antihypertensive); Penicillamine (used for the treatment of Wilson's disease and rheumatoid arthritis). Taking iron preparations such as that of Multivitamins + Iron (Sangobion KIDS+) and the previously mentioned medicines should be spaced by at least 2 hours.
Absorption of iron may be reduced in the presence of the following: Antacids and proton pump inhibitors which reduce stomach acidity.
Some food (e.g. wholegrain cereals, eggs and milk).
Oral neomycin (broad-spectrum antibiotic).
Calcium, zinc and oral magnesium salts.
Bicarbonates, carbonates, oxalates or phosphates by the formation of insoluble complexes.
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