Sangobion Forte Drug Interactions

The following food components may reduce the absorption of ferrous salts: tea, coffee, wholegrain cereals, eggs, milk, calcium and zinc supplements. Bicarbonates, carbonates, oxalates, or phosphates, may impair the absorption of iron by the formation of insoluble complexes.
The following drugs may reduce the absorption of ferrous salts: antacids, proton pump inhibitors and trientine.
Iron reduces the absorption of fluoroquinolones, tetracyclines, levodopa, carbidopa, entacapone, penicillamine, and cefdinir. Iron possibly reduces the absorption of eltrombopag.
Trimethoprim or sulfonamides, alone or in combination as co-trimoxazole, may reduce the effect of folic acid and this may be serious in patients with megaloblastic anemia.
Folic acid has been observed to reduce plasma levels of anticonvulsants, particularly phenytoin, phenobarbital and primidone and therefore patients should be carefully monitored by the physician and the anticonvulsant drug dose adjusted as necessary.
Antibiotics may interfere with the microbiological assay for serum and erythrocyte folic acid concentrations and may cause falsely low results.