RiteMED Levocetirizine Special Precautions

Patients with predisposing factors of urinary retention (e.g., spinal cord lesion, prostatic hyperplasia) should use levocetirizine with caution.
Concomitant use of levocetirizine with alcohol or other central nervous system (CNS) depressants should be avoided (see Interactions).
Caution should be observed in epileptic patients at risk of convulsions.
Levocetirizine should only be used during pregnancy when clearly needed.
Effects on Ability to Drive and Use Machine: Somnolence, fatigue and asthenia are associated with levocetirizine treatment. Patients should exercise caution when performing hazardous activities requiring mental alertness and physical coordination (e.g., driving, operating machinery).
Renal Impairment: Levocetirizine is mainly excreted by the kidneys and the risk of adverse effects may be greater in patients with renal impairment (see Dosage & Administration).
Use in Pregnancy: See Use in Pregnancy & Lactation section for further information.
Use in Lactation: See Use in Pregnancy & Lactation section for further information.
Use in the Elderly: Clinical experience with levocetirizine has not identified differences in responses between the elderly and younger patients. However, dose should be carefully selected for elderly patients, usually starting at the lowest dose due to greater frequency of decreased hepatic, renal, or cardiac function and of concomitant disease or other drug therapy.