RiteMED Glimepiride Drug Interactions

If the patient is taking glimepiride tablets with any of the following he/she is at a greater risk of the effects of hypoglycemia: ACE inhibitors (e.g., captopril, used to treat heart conditions); anabolic steroids and male sex hormones (e.g. testosterone); allopurinol (used to treat gout); aspirin; azapropazone (pain killer/anti-inflammatory); chloramphenicol (antibiotic); coumarin anticoagulants (thins the blood); cyclo-, tro- and iphosphamides (arthritis medicine); fenfluramine (appetite suppressant); fibrates (a group of lipid lowering drugs, e.g. fenofibrate); fluconazole (antifungal medicine); fluoxetine (used to treat depression and obsessive compulsive disorders); insulin and oral antidiabetic products; metformin (diabetic medicine); monoamine-oxidase inhibitors (e.g. phenelzine, used to treat depressive illness); oxyphenbutazone (arthritis medicine and anti-inflammatory); pentoxifylline (used to thin the blood); phenylbutazone (arthritis medicine); probenecid (gout medicine); an antibiotic group called quinolones (e.g. ciprofloxacin); rifampicin (antibiotic); sulphinpyrazone (used to treat gout); sulphonamides (e.g. sulfadiazine rheumatic fever medicine); sympatholytics (this is a general group of medicines often used to reduce blood pressure or help the heart, tell the doctor if patient is taking any medicine which might be a sympatholytic); tetracyclines (e.g. doxycycline, an antibiotic); tritoqualine (antihistamine to reduce inflammation); miconazole (antifungal medicine).
Patient should also tell the doctor if he/she is taking the following, he/she might need to readjust the dose or medicine: oestrogens and progestagens (female hormone replacement or the contraceptive "Pill"); saluretics, thiazide diuretics (water tablets); thyroid medicine (e.g. thyroxine); glucocorticoids (e.g. betamethasone used to treat inflammation); phenothiazine derivatives, chlorpromazine (e.g. trifluoperazine or pericyazine, used in mental diseases); sympathomimethics which can be used in a number of ways including to treat asthma (e.g. salbutamol) or as decongestants (e.g. ephedrine hydrochloride); nicotinic acid (used as a lipid lowering drug); laxatives (long term use); phenytoin (used to prevent seizures and fits); diazoxide (used to treat hypertension); glucagons (antidiabetic medicine); barbiturates (e.g. sodium amytal used to treat insomnia); rifampicin (an antibiotic); acetazolamide (used to treat glaucoma, fluid retention in the eye and also epilepsy).
H₂ antagonists (e.g. cimetidine, used to treat stomach ulcers), beta blockers (e.g. propranolol, an antihypertension medicine), clonidine (used to treat high blood pressure) and reserpine (used to treat mental illness) may affect the action of Glimepiride Tablets.
Make sure the doctor knows if patient is taking any of these drugs.