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Click on icon to see table/diagram/imageInterference with Laboratory Tests: Erythromycin may falsely elevate concentrations of urinary catecholamines, 17-hydroxycorticosteroids, and 17-ketosteroids.
The drug may interfere with colorimetric assays resulting in falsely elevated aspartate aminotransferase (AST) and alanine aminotransferase (ALT) concentrations. Falsely elevated AST concentrations without liver injury may result due to erroneous measurement of unidentified metabolites of erythromycin in colorimetric determinations.
Erythromycin may decrease serum folate assay results if a microbiologic method is used since the drug can inhibit the growth of Lactobacillus casei; results are unaffected if the chromatographic procedure of Landon is used.
The presence of erythromycin in the blood may interfere with the etiologic diagnosis of mycoplasma pneumonia by masking a rise in the titer of tetrazolium reduction inhibition neutralizing antibody to Mycoplasma pneumoniae.
