Dicycloverine hydrochloride.
Each tablet contains: Dicycloverine Hydrochloride, USP 10 mg.
Pharmacology: Dicycloverine hydrochloride is an antimuscarinic agent with effects similar to but much weaker than those of atropine. It also has a direct antispasmodic action on smooth muscles and reduces secretions, especially salivary and bronchial secretions. It also reduces perspiration, but has a little effect on biliary or pancreatic secretion. Dicycloverine hydrochloride is used in the gastrointestinal spasm, particularly that associated with the irritable bowel syndrome and is also given in association with antacids as adjunct in the treatment of peptic ulcer.
For the treatment of gastrointestinal spasms, irritable colon and spastic constipation.
Adults: 1 to 2 tablets three to four times daily dose not exceeding 40 mg, or, as prescribed by a physician.
If overdoses have been taken by mouth, the stomach should be emptied by aspiration and lavage or by induction of emesis. The giving of activated charcoal to reduce absorption prior to lavage has been suggested.
Infants less than 6 months, obstructive uropathy, obstructive disease of the gastrointestinal tract, paralytic ileus, intestinal atony, severe ulcerative colitis and myasthenia gravis.
Should be used with caution in patients with glaucoma, prostatic hypertrophy, hiatal hernia associated with reflux esophagitis.
Side effects of dicycloverine hydrochloride are dryness of the mouth, with difficulty in swallowing and talking, thirst, dilatation of the pupils (mydriasis) with loss of accommodation (cycloplegia) and photophobia, flushing and dryness of the skin, constipation and headache.
Toxic doses cause tachycardia, rapid respiration, hyperpyrexia and CNS stimulation marked by restlessness, confusion, excitement, paranoid and psychotic reactions, hallucinations and delirium and occasionally seizures and convulsion.
Store at temperatures not exceeding 30°C. Protect from light.
A03AA07 - dicycloverine ; Belongs to the class of synthetic anticholinergics, esters with tertiary amino group. Used in the treatment of functional bowel disorders.
RiteMED Dicycloverine HCl tab 10 mg
100's (P1,000/box, P10/tab)
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