
Laboratory Parameters: Diclofenac increases platelet aggregation time but does not affect bleeding time, plasma thrombin clotting time, plasma fibrinogen, or factors V and VII to XII. Statistically significant changes in prothrombin and partial thromboplastin times have been reported in normal volunteers. The mean changes were observed to be less than 1 second in both instances, and are unlikely to be clinically important.
Persistently abnormal or worsening renal, hepatic or hematological test values should be followed up carefully since they may be related to therapy.
Tell the doctor if the patient is taking other medicines, including vitamins, supplements, and herbal medicines.