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Use during Pregnancy: Teratogenic effects (umbilical hernia, cephalocele, cleft palate) have been observed among rabbits that were administered intramuscularly with betamethasone dipropionate. Safety has not been absolutely determined; therefore it should not be applied extensively or in large amounts or for a prolonged period of time.
Use during Lactation: It is not known whether topical administration of corticosteroids is excreted in breast milk. Studies in human have not been reported. On the other hand, systemic corticosteroids are secreted into breast milk that may cause unwanted effects in the infant such as growth suppression. Topical corticosteroids should not be applied on the breasts of a nursing mother.
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