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Risek Insta: In doses ranged up to 2400 mg, manifestations were variable, but included confusion, drowsiness, blurred vision, tachycardia, nausea, vomiting, diaphoresis, flushing, headache, dry mouth and other adverse reactions similar to those seen in normal clinical experience. No specific antidote for omeprazole overdosage is known.
Omeprazole is extensively protein bound and is, therefore, not readily dialyzable. In the event of overdosage, treatment should be symptomatic and supportive. In addition, a sodium bicarbonate overdose may cause hypocalcemia, hypokalemia, hypernatremia and seizures.
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