Rhea Mefenamic Acid Dosage/Direction for Use

Undesirable effects may be minimized by using the minimum effective dose for the shortest duration necessary to control symptoms.
The oral dosage form of mefenamic acid may be taken with food if gastrointestinal upset occurs.
Mild to moderate pain/rheumatoid arthritis/osteoarthritis in adults and adolescents over 14 years of age: 500 mg three times daily.
Dysmenorrhea: 500 mg three times daily, to be administered at the onset of menstrual pain and continued while symptoms persist according to the judgment of the physician.
Menorrhagia: 500 mg three times daily, starting with the onset of bleeding and associated symptoms and continued according to the judgment of the physician.
Premenstrual syndrome: 500 mg three times daily, starting with the onset of symptoms and continued until the anticipated cessation of symptoms according to the judgment of the physician.
Use in the Elderly: Impairment of renal function, sometimes leading to acute renal failure, has been reported. Elderly or debilitated patients seem unable to tolerate ulceration or bleeding as well as some other individuals; most spontaneous reports of fatal gastrointestinal events are in this patient population (see Gastrointestinal (GI) Effects under Precautions).