Reform Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Metformin HCl

Indications/Uses

Initial monotherapy or w/ sulphonylurea for diet-failed NIDDM.

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Dosage/Direction for Use

NIDDM Initially 500 mg bid or tid or 850 mg once daily or bid. May gradually increase to a max dose of 2-3 g daily.

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Overdosage

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Administration

Should be taken with food.

Contraindications

Diabetic coma, ketoacidosis, impaired renal function, chronic liver disease. Cardiac failure, recent MI, alcoholism, tissue hypoxia, lactic acidosis. Severe infections, trauma, surgery, dehydration.

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Special Precautions

Not to be used in IDDM; patients w/ heart failure, dehydration, acute or chronic alcoholism, or any other condition likely to predispose to lactic acidosis. Associated w/ increased risk of congenital abnormalities & perinatal mortality. Not recommended during breast-feeding.

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Use In Pregnancy & Lactation

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Adverse Reactions

Anorexia, nausea, & vomiting; impaired absorption of various substances including vit B₁₂. Metallic taste; wt loss. Lactic acidosis.

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Drug Interactions

Increased risk of hypoglycemia w/ drugs that lower blood glucose conc. Reduced effect of biguanide therapy w/ drugs that increase blood glucose conc. Increased risk of lactic acidosis & hypoglycaemia w/ alcohol. Concomitant use w/ drugs that may impair renal function.

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Storage

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Description

View Reform description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Antidiabetic Agents

ATC Classification

A10BA02 - metformin ; Belongs to the class of biguanides. Used in the treatment of diabetes.

Regulatory Classification

Presentation/Packing

Form

Reform FC tab 500 mg

Packing/Price

100's

Reform

metformin

Manufacturer:

Lloyd

Distributor:

Pharma Dynamic