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After addition of the solvent to the freeze-dried substance, the solution should be given immediately by intramuscular injection. Any unused solution should be discarded. Self-administration of PUBERGEN should only be performed by patients who are well-motivated, adequately trained and with access to expert advice.
In Females: The dosage regimen employed in any particular case will depend upon the indication for use, the age and weight of the patients, and the physician's preference. The following regimens have been advocated by various authorities. Induction of ovulation and pregnancy in the anovulatory, infertile woman in whom the cause of anovulation is secondary and not due to primary ovarian failure.
5,000 IU to 10,000 IU one injection on 12th day of menstrual cycle or when the Graafian follicle attains a size ≥18 mm.
In Males: Chorionic Gonadotropin (Pubergen) 5,000 IU twice weekly for 12 weeks sand may have to be continued even up to 1 year to improve semen quality.
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