Prolix Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Prednisone

Indications/Uses

Endocrine, nervous, CV, renal (eg, nephrotic syndrome), GI, skin & integumentary systems, ocular & resp system of inflammatory & allergic origin (eg, bronchial asthma & skin allergies). Susp: Rheumatic, collagen, neoplastic, hematologic & autoimmune disorders eg, autoimmune hemolytic anemia, idiopathic thrombocytopenic purpura, inflammatory bowel diseases, SLE & some case of Hashimoto's thyroiditis.

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Dosage/Direction for Use

5-60 mg daily in divided doses or as a single daily morning dose or as a double dose on alternate days. Tab Immunosuppressive 10-100 mg daily. Primary & secondary adrenocortical insufficiency 5-25 mg daily in divided doses. Adrenogenital syndromes 10-20 mg/m² daily in divided doses.

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Overdosage

View Prolix overdosage for action to be taken in the event of an overdose.

Administration

Should be taken with food.

Contraindications

Systemic fungal infections, glaucoma, gastric & duodenal ulcers, certain viral infections & severe psychoneuroses.

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Special Precautions

Heart disease, HTN, renal dysfunction, peptic ulcer, systemic fungal infection, history of psychotic disorders, diabetes, TB, osteoporosis, glaucoma, myasthenia gravis, diverticulitis, colitis & viral diseases like herpes. Monitor adverse effects eg, hyperglycemia, glucosuria, Na retention w/ edema, HTN, osteoporosis & fungal infection in patients receiving high dose or on long-term therapy. Avoid abrupt discontinuation of treatment.

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Use In Pregnancy & Lactation

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Adverse Reactions

Adrenal suppression; GI distress, nausea, peptic ulcer, behavioral disturbances, fluid & electrolyte imbalance, visual disturbances, growth retardation, skin atrophy, moon face, Cushingoid state, hirsutism & muscle atrophy.

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Drug Interactions

Reduced effect w/ anticonvulsants, phenobarb, phenytoin, antihistamines, barbiturates, ephedrine, primidone & rifampicin. May reduce the efficacy of hypoglycemics, diuretics, salicylates & anticholinesterases. Enhanced effect w/ aspirin & estrogen. Cyclosporine.

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Storage

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Description

View Prolix description for details of the chemical structure and excipients (inactive components).

Action

View Prolix mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Corticosteroid Hormones

ATC Classification

H02AB07 - prednisone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.

Regulatory Classification

Presentation/Packing

Form

Prolix oral susp 10 mg/5 mL

Packing/Price

60 mL x 1's (P140.34/bottle)

Form

Prolix tab 20 mg

Packing/Price

100's (P750/pack)

Prolix

prednisone

Manufacturer:

Lloyd

Distributor:

PNSV Asia