PROFUREX is indicated for (1) prophylaxis against infection to abdominal, pelvic, orthopedic, cardiac, pulmonary, esophageal, and vascular surgery where there is increased risk of infection; (2) respiratory tract infections, e.g. acute and chronic bronchitis, infected bronchiectasis, bacterial pneumonia, lung abscesses, and post-operative chest infections; (3) ear, nose and throat infections, e.g. sinusitis, tonsilitis, and pharyngitis; (4) urinary tract infections like acute or chronic pyelonephritis, cystitis; (5) soft tissue infections like cellulitis, erysipelas, peritonitis; (6) bone and joint infections like osteomyelitis and septic arthritis; (7) obstetric and gynecologic infection, pelvic inflammatory diseases; (8) gonorrhea particularly when penicillin is unsuitable; (9) other infections including septicemia and meningitis.