Prenat Special Precautions

Iron: Should not be given to patients receiving repeated blood transfusions or to patients with anemias not produced by iron deficiency unless iron deficiency is also present. Oral iron therapy should not be administered concomitantly with parenteral iron. Care should be taken in patients with iron-storage or iron-absorption diseases such as hemochromatosis, hemoglobinopathies, or existing gastrointestinal diseases such as inflammatory bowel disease, intestinal strictures and diverticulae.
Folic Acid: Should never be given alone or in conjunction with inadequate amounts of vitamin B12 for the treatment of undiagnosed megaloblastic anemia, since folic acid may produce a hematopoietic response in patients with a megaloblastic anemia due to vitamin B12 deficiency without preventing aggravation of neurological symptoms. This masking of the true deficiency state can lead to serious neurological damage, such as subacute combined degeneration of the spinal cord.