Prazole Forte/Prazole IV Dosage/Direction for Use

Prazole Forte: Gastro-oesophageal reflux disease: 20 to 40 mg once daily for 4-8 weeks.
For maintenance therapy: 20-40 mg daily.
Peptic ulcer disease: 40 mg once daily.
Duodenal ulceration: 40 mg once daily for 2 to 4 weeks.
Benign gastric ulceration: 40 mg once daily for 4 to 8 weeks.
For the eradication of Helicobacter pylori: Pantoprazole may be combined with two antibacterials in a 1-week triple therapy regimen.
Effective regimens include Pantoprazole 40 mg daily twice daily combined with Clarithromycin 500 mg twice daily and either Amoxicillin 1g twice daily or Metronidazole 400 mg twice daily.
Prophylaxis for NSAID-associated ulceration: 20 mg daily.
Zollinger-Ellison syndrome: 80 mg daily, given in 2 divided doses.
Or as directed by the physician.
Prazole IV: Recommended Dose: 40 mg IV once daily for 7 days.
Duodenal Ulcer: Duodenal ulcers generally heal within 2 weeks. If a 2-week period of treatment is not sufficient, healing will be achieved in almost all cases within a further 2 weeks.
Gastric Ulcer and Gastroesophageal Reflux: A 4-week period is usually required for the treatment of gastric ulcers and gastroesophageal reflux. If this is not sufficient, healing will usually be achieved in within a further 4 weeks.
Administration: For IV administration only. Prazole IV is recommended only in cases where the oral administration is not indicated. The content of the vial needs to be reconstituted with 0.9% sodium chloride injection w/v 10 mL before injection. This freshly prepared solution should be administered IV over 2-15 min, either as a slow injection or it may be further diluted with 0.9% sodium chloride injection w/v 100 mL or 5% glucose injection and administered as a short-term infusion. The duration of administration should be 2-15 min. The reconstituted solution must be used within 12 hrs of preparation.