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The formulation contains vitamins B1, B6 and B12 which are all water soluble. Any excess intake will be readily eliminated in the urine. Sensitivity to vitamin B1 may sometimes be encountered. Sensitivity may occur if administration is at prolonged intervals, is irregular, or if the initial dose is low and is suddenly increased. Liver dysfunction also seems to predispose patients to hypersensitivity reactions. Nevertheless, it must be stressed that hypersensitivity to vitamin B1 is very rare when given orally and is encountered more often only when given by intravenous injection.
Paracetamol is generally safe and well tolerated. Rashes and other transient and mild allergic reactions may be occasionally encountered.
