Oxtimon Side Effects

As there is a wide variation in uterine sensitivity, uterine spasm may be caused in some instances by what are normally considered to be low doses. When Oxytocin Injection is used by IV infusion for the induction or enhancement of labour, its administration at too high doses results in uterine overstimulation which may cause fetal distress, asphyxia, and death, or may lead to hypertonicity, tetanic contractions, soft tissue damage or rupture of the uterus. Water intoxication associated with maternal and neonatal hyponatremia has been reported in cases where high doses of oxytocin together with large amounts of electrolyte-free fluid have been administered over a prolonged period of time (see Precautions).
Symptoms of water intoxication include: Headache, anorexia, nausea, vomiting and abdominal pain.
Lethargy, drowsiness, unconsciousness and grand-mal type seizures.
Low blood electrolyte concentration.
Rapid intravenous bolus injection of oxytocin at doses amounting to several I.U. may result in acute short-lasting hypotension accompanied with flushing and reflex tachycardia. Oxytocin may occasionally cause nausea, vomiting or cardiac arrhythmias. In a few cases, skin rashes and anaphylactoid reactions associated with dyspnea, hypotension, or shock have been reported.