Orphex Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Paracetamol 450 mg, orphenadrine citrate 35 mg

Indications/Uses

Painful skeletal muscle spasm associated w/ chronic low back pain, sprains & strains, prolapsed intervertebral disc, muscle injury, non-articular rheumatism, whiplash injury, acute torticollis, tension headache, dysmenorrhea & other painful muscular conditions.

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Dosage/Direction for Use

1-2 tab tid.

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Overdosage

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Administration

May be taken with or without food: May be taken w/ meals if GI discomfort occurs.

Contraindications

Glaucoma; myasthenia gravis; prostatic hypertrophy or bladder neck obstruction. Childn <12 yr.

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Special Precautions

Cardiac arrhythmias, tachycardia, cardiac decompensation, coronary insufficiency. Monitor blood, urine & liver function w/ prolonged use. May impair the ability to drive or operate machinery. Pregnancy & lactation.

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Use In Pregnancy & Lactation

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Adverse Reactions

Dry mouth, nausea, constipation, tachycardia, palpitation, urinary hesitancy or retention, blurred vision, mydriasis, increased ocular tension, weakness, headache, dizziness & drowsiness.

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Drug Interactions

Increased paracetamol absorption w/ metoclopramide & domperidone. Decreased paracetamol absorption w/ cholestyramine. May increase risk of bleeding w/ warfarin & coumarins. Increased anticholinergic side effects w/ other anticholinergic drugs. Additive CNS effects w/ propoxyphene. Increased bupropion levels. May antagonize actions of centrally-acting anticholinesterases eg, donepezil, galantamine, rivastigmine, tacrine. May decrease levodopa absorption. Increased risk of liver damage w/ alcohol.

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Storage

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Description

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Action

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MIMS Class

Analgesics (Non-Opioid) & Antipyretics / Muscle Relaxants

ATC Classification

M03BC51 - orphenadrine, combinations ; Belongs to the class of ethers. Used as centrally-acting muscle relaxants.

Regulatory Classification

Presentation/Packing

Form

Orphex tab

Packing/Price

30's

Orphex

orphenadrine + paracetamol

Manufacturer:

Nutramedica

Distributor:

Nutramedica