Tab Adult 8 mg up to 2 hr before treatment followed by 8 mg to 12 hr later.
Delayed emesis 8 mg bid for up to 5 days after the end of a course of chemotherapy.
Childn 4-11 yr 4 mg 30 min before start of chemotherapy, w/ subsequent 4 mg given 4 & 8 hr thereafter. 4 mg tid may be given 1-2 days after the end of chemotherapy.
Prevention & treatment of post-op nausea & vomiting Adult 8 or 16 mg 1 hr before anaesth followed by 2 further doses of 8 mg at 8-hr interval.
Renal impairment Should not exceed 8 mg.
Inj Prevention of PONV Adult 4 mg (undiluted) IV or IM as a single inj.
Ped patients 1 mth-12 yr 4 mg single dose for patients weighing >40 kg. A single dose of 0.1 mg/kg for patients weighing <40 kg. Administration: The rate of administration should not be less than 30 sec over 2-5 min immediately prior to or following anesth induction, or post-op if patient did not receive prophylactic antiemetics & experiences nausea &/or vomiting occur shortly after surgery.