Noxadium 4000/Noxadium 6000 Dosage/Direction for Use

All patients should be evaluated for a bleeding disorder before administration of Enoxaparin, unless the medication is needed urgently, or as prescribed by the physician.
Abdominal surgery: In patients undergoing abdominal surgery who are at risk for thromboembolic complications, the recommended dose of Enoxaparin is 40 mg once a day administered by SC injection with the initial dose given 2 hours prior to surgery. The usual duration of administration is 7 to 10 days; up to 12 days administration has been well tolerated in clinical trials.
Hip or Knee Replacement surgery: In patients undergoing hip or knee replacement surgery, the recommended surgery dose of enoxaparin is 30 mg every 12 hours administered by SC injection. Provided that hemostasis has been established, the initial dose should be given 12 to 24 hours after surgery.
For hip replacement surgery, a dose of 40 mg once a day SC is given initially 12 hours prior to surgery may be considered. The initial phase of thromboprophylaxis in hip replacement surgery patients, continued prophylaxis with Enoxaparin 40 mg once a day administered by SC injection for 3 weeks is recommended. The usual duration of administration is 7 to 10 days; up to 14 days administration has been well tolerated in clinical trials.
Medical Patients During Acute illness: In medical patients at risk for thromboembolic complications due to severely restricted mobility during acute illness, the recommended dose of Enoxaparin is 40 mg once a day administered by SC injection. The usual duration of administration is 6 to 11 days up to 14 days of Enoxaparin has been well tolerated in the controlled clinical trial.
Administration: Enoxaparin is a clear, colorless to pale yellow sterile solution, and as with other parenteral drug products, should be inspected visually for particulate matter and discoloration prior to administration.
Enoxaparin is administered by SC injection. It must not be administered by intramuscular injection. Enoxaparin is intended for use under the guidance of a physician. Patients may self-inject only if their physician determines that it is appropriate and with medical follow-up, as necessary. Proper training in subcutaneous injection technique (with or without the assistance of an injection device) should be provided.
Subcutaneous Injection Technique: Patients should be lying down and enoxaparin administered by deep SC injection. To avoid the loss of drug do not expel the air bubble from the syringe before the injection. Administration should be alternated between the left and right anterolateral and left and right posterolateral abdominal wall. The whole length of the needle should be introduced into a skin fold held between the thumb and forefinger; the skin fold should be held throughout the injection. To minimize bruising, do not rub the injection site after completion of the injection.