Vitamin C should not be given for the first month after starting desferrioxamine treatment since it may worsen the iron toxicity. Large supplements of vitamin C may increase serum ethinylestradiol concentrations in women taking oral contraceptives. Giving vitamin C to patient receiving fluphenazine for bipolar disorder was associated with a fall in serum concentrations of fluphenazine and a deterioration of behavior. Concomitant vitamin C taken with warfarin may reduce the activity of warfarin. Vitamin C may increase the absorption of iron in iron-deficiency states.
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