Mosaspray Dosage/Direction for Use

Dosage and mode/route of administration: After initial priming each actuation delivers 50 μg mometasone furoate.
Dosage: Seasonal allergic or perennial rhinitis: Adults (including older patients) and children 12 years of age and older:The usual recommended dose is two actuations (50 μg/actuation) in each nostril once daily (total dose 200 μg). Once symptoms are controlled, dose reduction to one actuation in each nostril (total dose 100 μg) may be effective for maintenance.
If symptoms are inadequately controlled, the dose may be increased to a maximum daily dose of four actuations in each nostril once daily (total dose 400 μg). Dose reduction is recommended following control of symptoms.
Children between the ages of 3 and 11 years: The usual recommended dose is one actuation (50 μg/actuation) in each nostril once daily (total dose 100 μg).
Mometasone furoate nasal spray demonstrated a clinically significant onset of action within 12 hours after the first dose in some patients with seasonal allergic rhinitis; however, full benefit of treatment may not be achieved in the first 48 hours. Therefore, the patient should continue regular use to achieve full therapeutic benefit.
Treatment with mometasone furoate nasal spray may need to be initiated some days before the expected start of the pollen season in patients who have a history of moderate to severe symptoms of seasonal allergic rhinitis.
Nasal polyposis: The usual recommended starting dose for polyposis is two actuations (50 μg/actuation) in each nostril once daily (total daily dose of 200 μg). If after 5 to 6 weeks symptoms are inadequately controlled, the dose may be increased to a daily dose of two sprays in each nostril twice daily (total daily dose of 400 μg). The dose should be titrated to the lowest dose at which effective control of symptoms is maintained. If no improvement in symptoms is seen after 5 to 6 weeks of twice daily administration, the patient should be re-evaluated and treatment strategy reconsidered.
Efficacy and safety studies of mometasone furoate nasal spray for the treatment of nasal polyposis were four months in duration.
Paediatric population: Seasonal allergic rhinitis and perennial rhinitis: The safety and efficacy of mometasone furoate nasal spray in children under 3 years of age have not been established.
Nasal polyposis: The safety and efficacy of mometasone furoate nasal spray in children and adolescents under 18 years of age have not been established.
Method of administration: Prior to administration of the first dose, shake container well and actuate the pump 10 times (until a uniform spray is obtained). If the pump is not used for 14 days or longer, reprime the pump with 2 actuations until a uniform spray is observed, before next use.
Shake container well before each use. The bottle should be discarded after the labelled number of actuations or within 2 months of first use.
Preparing the nasal spray for use: Mometasone furoate Nasal Spray has a dust cap which protects the nozzle and keeps it clean. Take this off before using the spray and replace it after use.
If to be used for the first time, 'prime' the bottle by pumping the spray 10 times until a fine mist is produced: 1. Shake the bottle well.
2. Put the forefinger and middle finger on either side of the nozzle and the thumb underneath the bottle.
3. Point the nozzle away and then press down with fingers to pump the spray.
If not used for 14 days or more, "re-prime" the bottle by pumping the spray twice until a fine mist is produced.
At the usual dose of 2 sprays into each nostril once daily, this medicine should provide enough doses for 35 days (140 sprays).
How to use the nasal spray: 1. Shake the bottle well and remove the dust cap.
2. Gently blow nose.
3. Close one nostril and put the nozzle into the other nostril.
4. Tilt head forward slightly, keeping the bottle upright.
5. Start to breathe in gently or slowly through the nose and whilst breathing in squirt a spray of fine mist into the nose by pressing down ONCE with fingers.
6. Breathe out through the mouth. Repeat step 5 to inhale a second spray in the same nostril.
7. Remove the nozzle from this nostril and breathe out through the mouth.
8. Repeat steps 3 to 7 for the other nostril.
After using the spray, wipe the nozzle carefully with a clean handkerchief or tissue and replace the dust cap.
Cleaning the nasal spray: It is important that the nasal spray is cleaned regularly, otherwise it may not work properly. Remove the dust cap and gently pull off the nozzle. Wash the nozzle and dust cap in warm water and then rinse under a running tap. Allow to dry in a warm place. Push the nozzle back onto the bottle and replace the dust cap. The spray will need to be re-primed with 2 sprays when first used after cleaning.