Monowel Caution For Usage

Preparation of Solution: For intravenous use, 1 g should be constituted with at least 10 mL of Sterile Water for Injection, and 2 g with 10 or 20 mL. 1 g or 2 g of cefoxitin sodium for infusion may be constituted with 50 or 100 mL of 0.9% Sodium Chloride Injection, 5% or 10% Dextrose Injection, or any of the solutions listed under Compatibility and Stability.
Compatibility and Stability: The compatibility and stability of Cefoxitin sodium (Monowel) in solution with the following frequently used intravenous infusion fluids and injectable additives have been established: 0.9% Sodium Chloride Injection, 5% or 10% Dextrose Injection, 5% Dextrose and 0.9% Sodium Chloride Injection, 5% Dextrose Injection with 0.02% Sodium bicarbonate solution, 5% Dextrose Injection with 0.2% or 0.45% saline solution, Lactated Ringer's Injection, 5% Dextrose in Lactated Ringer's Injection, 5% or 10% Invert sugar in water, 10% Invert sugar in saline solution, 5% Sodium Bicarbonate Injection, M/6 Sodium Lactate solution, Insulin in normal saline
Insulin in 10% invert sugar, Heparin, 100 units/ml and 0.1 unit/ml, Mannitol 2.5% and 5%, Mannitol 10%.
Cefoxitin sodium (Monowel) has been shown chemically and visually compatible with aminoglycosides such as amikacin, gentamycin, kanamycin and tobramycin when admixed in 200 mL of 0.9% Sodium Chloride or 5% Dextrose in Water.