Metcort Overdosage

Symptoms: As the clinically effective dose of corticosteroids vary according to the indications and requirements of individual patients, it is difficult to define "excessive" dosage of corticosteroids. Reports of acute toxicity and/or death resulting from corticosteroid overdosage are rare. However, continued use of large doses of corticosteroids (which are often necessary to elicit a clinical response) without proper dose reduction, leads to exaggeration of usual corticosteroid-related problems and aggravate preexisting disease states (ie, ulceration of the gastrointestinal tract, electrolyte disturbances, infections, diabetes and edema).
Treatment: There is no known specific antidote available. Treatment of acute overdose is symptomatic and supportive (including respiratory and cardiovascular function). In case of chronic toxicity, closely monitor fluids and electrolytes levels. Serum levels are not clinically useful.
Methylprednisolone is dialyzable.