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Muscarinic-type side effects can manifest themselves as nausea, vomiting, diarrhea, stomach cramps, increased peristalsis and bronchial secretion, salivation and lacrimation, as well as bradycardia and miosis. Nicotine-type side effects consist mainly of muscle spasms, muscle twitches and muscle weakness.
Like other bromine-containing drugs, Mestinon can occasionally cause skin rash, though this generally disappears rapidly after medication has been discontinued. Further use of Mestinon or other bromine-containing preparations is then contraindicated.
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