AdultPneumonia, UTI, gynecological infections eg, endometritis, pelvic inflammatory disease, skin & skin structure infections 500 mg IV every 8 hr. Nosocomial pneumonias, peritonitis, presumed infections in neutropenic patient & septicemia 1 g IV every 8 hr. Meningitis & lung infections in patient w/ cystic fibrosis 2 g every 8 hr. Childn >50 kg Adult dose. Childn >3 mth & up to 12 yr 10-40 mg/kg every 8 hr. Meningitis & cystic fibrosis 40 mg/kg every 8 hr. Neutropenic patient w/ fever 20 mg/kg every 8 hr. Administered as IV bolus inj over approx 5 min or IV infusion over approx 15-30 min. Renal impairment w/ CrCl 26-50 mL/min 1 unit dose every 12 hr; 10-25 mL/min ½ unit dose every 12 hr; <10 mL/min ½ unit dose every 24 hr.
Overgrowth of nonsusceptible organisms may occur. Not use for methicillin-resistant staphylococci infections. Consider diagnosis of pseudomembranous colitis in patients who develop diarrhea. Co-administration w/ potentially nephrotoxic drugs. Pregnancy & lactation. Not recommended in infant <3 mth.
Sign Out
