M-M-R II Description

MEASLES, MUMPS, AND RUBELLA VIRUS VACCINE LIVE (M-M-R II) is a live virus vaccine for vaccination against measles (rubeola), mumps, and rubella (German measles).
MEASLES, MUMPS, AND RUBELLA VIRUS VACCINE LIVE (M-M-R II) is a sterile lyophilized preparation of (1) MEASLES VIRUS VACCINE LIVE (ATTENUVAX), a more attenuated line of measles virus, derived from Enders' attenuated Edmonston strain and propagated in chick embryo cell culture; (2) MUMPS VIRUS VACCINE LIVE (MUMPSVAX), the Jeryl Lynn (B level) strain of mumps virus propagated in chick embryo cell culture; and (3) RUBELLA VIRUS VACCINE LIVE (MERUVAX II), the Wistar RA 27/3 strain of live attenuated rubella virus propagated in WI-38 human diploid lung fibroblasts.
The reconstituted vaccine is for subcutaneous administration. When reconstituted as directed, the dose for injection is 0.5 mL and contains not less than 1,000 CCID₅₀ (50% cell culture infectious dose) of measles virus 12,500 CCID₅₀ of mumps virus; and 1,000 CCID₅₀ of rubella virus. Each dose of the vaccine is calculated to contain sorbitol (14.5 mg), sodium phosphate, sucrose (1.9 mg), sodium chloride, hydrolyzed gelatin (14.5 mg), recombinant human albumin (≤0.3 mg), fetal bovine serum (<1 ppm), other buffer and media ingredients and approximately 25 mcg of neomycin. The product contains no preservative.