
Special Population: Patients with Renal Impairment: See Table 3.

Neonates and infants ≤3 months: 20 to 30 mg/kg/day in divided doses every 12 hours.
Usual Duration of Treatment: For most infections: 5 to 14 days, depending on the type and severity of infection. Continue treatment for at least 48 to 72 hours after the patient becomes asymptomatic or after evidence of bacterial eradication has been continued.
For β-hemolytic streptococcal infections: At least 10 days to prevent rheumatic fever or glomerulonephritis.
For Lyme Disease: At least 12 days.
*Frequent bacteriologic and clinical appraisal is necessary during treatment of chronic urinary tract infections and maybe required for several months after therapy has been completed.