Lipway: In combination with diet, this drug constitutes a long-term symptomatic treatment, the efficacy of which should be assessed regularly.
Adults: For the management of primary hypercholesterolemic or mixed dyslipidemia: The recommended initial dosage of fenofibrate is 160 mg daily.
For the management of elevated serum triglyceride concentrations: The recommended initial dosage of fenofibrate in adults is 54-160 mg daily.
Dosage should be adjusted at intervals of 4-8 weeks until the desired effect on lipoprotein concentrations is observed or a maximum dosage of 160 mg daily.
Fenofibrate should be discontinued in patients who fail to achieve an adequate response after 2-3 months of therapy with the maximum recommended dosage of 160 mg daily.
Tablets should be swallowed whole during a meal.
Special Populations: The recommended initial dosage of fenofibrate for the management of hyperlipoproteinuria in patients 65 years of age or older and in those with renal impairment (creatinine clearance less than 50 mL/minute) is 54 mg daily. Dosage should be adjusted only after evaluating therapeutic response and the effects of the drug on renal function.
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