Levophed SF Caution For Usage

Special Precautions for Disposal and Other Handling: Dilution instructions: Dilute before use with glucose 5% solution or sodium chloride 9 mg/mL (0.9%) with glucose 5% solution.
Either add 2 mL concentrate to 48 mL glucose 5% solution (or sodium chloride 9 mg/mL (0.9%) with glucose 5% solution) for administration by syringe pump, or add 20 mL of concentrate to 480 mL glucose 5% solution (or sodium chloride 9 mg/mL (0.9%) with glucose 5% solution) for administration by drip counter. In both cases the final concentration of the infusion solution is 40 mg/L noradrenaline base (which is equivalent to 80 mg/liter noradrenaline tartrate). Dilutions other than 40 mg/L noradrenaline base may also be used (see Titration of dose under Dosage & Administration). If dilutions other than 40 mg/L noradrenaline base are used, check the infusion rate calculation carefully before starting treatment.
The product is compatible with PVC infusion bags.
Any unused medicinal product or waste material should be disposed of in accordance with local requirements.
Incompatibilities: Noradrenaline must not be mixed with other medicinal products except those mentioned in Special Precautions for Disposal and Other Handling previously.
Infusion solutions containing noradrenaline tartrate have been reported to be incompatible with the following substances: alkalis and oxidizing agents, barbiturates, chlorpheniramine, chlorothiazide, nitrofurantoin, novobiocin, phenytoin, sodium bicarbonate, sodium iodide, streptomycin.
For compatibility with infusion bags see Special Precautions for Disposal and Other Handling as mentioned previously.